Searchable abstracts of presentations at key conferences in endocrinology

ea0093oc30 | Oral communication 5: Reproductive Endocrinology | EYES2023

Quantification of 27 sex hormones, precursors and metabolites thereof in human plasma by a mass spectrometry-based method combining direct detection and specific hydrolysis of glucuronide conjugates

Raps Miriam , Kleider Carolin , Pemp Daniela , Lehmann Leane

Background: Steroid hormones such as the estrogen 17β-estradiol and the androgen testosterone play an important role in the etiology of hormone dependent diseases. To investigate factors influencing endogenous steroid hormone synthesis also biologically less active glucuronides and sulfates should be considered since they can serve as circulating reservoir for bioactive hormones. As the sensitivity of the available mass spectrometry (MS)-based method is lower for glucuron...